Asian Pacific Journal of Tropical Biomedicine
Red propolis: Chemical composition and pharmacological activity
Luciane CorbelliniRufatto1
Denis Amiltondos Santos2
FlávioMarinho1
João Antonio PêgasHenriques2
MarianaRoesch Ely2
SidneiMoura1
Laboratory of Biotechnology of Natural and Synthetics Products – Biotechnology Institute, University of Caxias do Sul, Brazil
Laboratory of Genomics, Proteomics and DNA Repair – Biotechnology Institute, University of Caxias do Sul, Brazil
Abstract
Propolis has been used worldwide for years in folk medicine and currently marketed by the pharmaceutical industry. In Brazil, propolis was classified into 13 groups based on their organoleptics and physicochemical characteristics. The 13th type named red propolis has been an important source of investigation since late 90s. Their property comes from the countless compounds, including terpenes, pterocarpans, prenylated benzophenones and especially the flavonoids. This last compound class has been indicated as the responsible for its potent pharmacological actions, highlighting the antimicrobial, anti-inflammatory, antioxidant, healing and antiproliferative activities. The red propolis can also be found in other countries, especially Cuba, which has similar features as the Brazilian. Therefore, with the compilation of 80 papers, this review aims to provide a key reference for researchers interested in natural products and discovery of new active compounds, such as from propolis.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.