Comparative antiproliferation of human prostate cancer cells by ethanolic extracts of two groups of Brazilian propolis
Cleber Silveira MORAES1, Andreas DAUGSCH1, Hongzhen LI2, Johng Suk RHIM2, Yong Kun PARK1*
1 Department of Food Science, College of Food Engineering, State University of Campinas – UNICAMP, CEP 13081-970, P.O. Box 6177, Campinas – SP, Brazil,
2 Center for Prostate Disease Research, Uniformed Services University of the Health Sciences – USUHS, Bethesda – MD, USA
Two groups of propolis, group 12, which was collected in the southeastern Brazil and group 13, which was collected in the northeastern Brazil, were examined for antiproliferation of primary malignant tumor (RC-58T/h/SA#4)-derived human prostate cancer cells and human prostate epithelial cells. The strongest inhibition of RC-58T/h/SA#4 cells was observed in propolis group 13 extracts, whereas moderate growth inhibition was observed in human prostate epithelial cells in comparison with group 12. It can be said that the Brazilian propolis of group 13 contains important chemical ingredients.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.