Effect of xylitol chewing gum enriched with propolis on dentin remineralization in vitro.

Wafa Gargouria, Rym Kammounb, Mazen Elleuchec, Mahdi Tlilib, Nabil Kechaoua, Sonia Ghoul-Mazgarb

Abstract

Objectives

The aim of this study was to evaluate the efficiency of xylitol chewing gums enriched with propolis, remineralizing softly demineralized dentin in vitro.

Design

Four groups of chewing gum were developed; Group1: xylitol (1.8 %), Group2: xylitol + casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) (3%), Group3: xylitol+Hydroxyapatite (3%) and Group4: xylitol + propolis (5%). A control group was designed without chewing gum, but with artificial saliva. Sections of embedded crowns and cleaned roots of twenty five bovine incisors were demineralized in carbonated drink. Crown specimens were half-varnished. Remineralization process was run for all the dental specimens in the 4 groups with gum extracts and in the control group with artificial saliva for 20 min at 37 °C three times a day during 7 days. Mineral contents were evaluated by scanning electron microscopy with energy dispersive X-ray spectroscopy (EDX-SEM). Surface morphology and roughness were analyzed using atomic force microscopy (AFM). Micro-hardness was measured using Vickers micro-hardness tester among varnished and unvarnished sides.R

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.