Clinical and Experimental Otorhinolaryngology > Volume 11(2); 2018 > Article
Clinical and Experimental Otorhinolaryngology 2018; 11(2): 146-150.
Published online: December 28, 2017
DOI: https://doi.org/10.21053/ceo.2017.00647
Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study
Jeong Hwan Moon, Min Young Lee, Young-Jun Chung, Chung-Ku Rhee, Sang Joon Lee,
Corresponding author: Sang Joon Lee
Received June 2, 2017 Revised August 24, 2017 Accepted September 27, 2017
Copyright © 2018 by Korean Society of Otorhinolaryngology-Head and Neck Surgery
Abstract
Objectives
The post-tonsillectomy pain and post-tonsillectomy hemorrhage are the two main problems after tonsillectomy. The aim of this study was to investigate the beneficial effects of water soluble ethanol extract propolis on post-tonsillectomy patient.
Methods
One hundred and thirty patients who underwent tonsillectomy or adenotonsillectomy were randomly divided into the control and propolis groups, each including 65 patients. The propolis group was applied with propolis orally immediately after surgery and by gargle. The pain scores were assessed on post-tonsillectomy 0, 1st, 2nd, 3rd, and 7th–10th day using a visual analogue scale score. Postoperative wound healing was evaluated by scoring pinkish membrane of tonsillar fossae on postoperative days 3 and 7–10. The incidence of post-tonsillectomy bleeding was examined in each group.
Results
Post-tonsillectomy pain was significantly less in propolis group compared to control group on postoperative days 3 and 7–10. Post-tonsillectomy hemorrhage was significantly less in the propolis group compared to the control group (P<0.05). The wound healing was significantly better in the propolis group compared to the control group on postoperative day 7–10 (P=0.002).
Conclusion
Applying the propolis to post-tonsillectomy wound showed beneficial effect of reducing postoperative pain, preventing hemorrhage, and accelerating of wound healing of tonsillar fossae.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.