Organic Chemistry

Chemical constituents of Brazilian Propolis from the state of Bahia and their growth inhibitory activities against cancer cells.

Taichi Mitsui , Sho Hotta, Shigemi Tazawa, Yasuko Arai, Kenji Kato & Kenji Ichihara

Pages 1-5 | Received 05 Dec 2017, Accepted 05 Jan 2018, Published online: 26 Jan 2018

Abstract

A novel 2-phenoxychromone (1) and five known flavones (2-6) were isolated from northeastern Brazilian propolis in the state of Bahia. The chemical structures of these six compounds were determined by spectroscopic investigations and single-crystal X-ray analysis. The isolated compounds showed growth-inhibitory activities, in varying degrees, against human tumor cell lines. This is the first report on the discovery of a novel 2-phenoxychromone from propolis.

A novel 2-phenoxychromone (1) and five known flavones (2–6) were isolated from Brazilian propolis in the state of Bahia.

 

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.