Yuanyuan Gu, Chunshui Cao, Jian Liu, Yong Liu, Liang Huang & Zuan Zhan
Abstract
Background
In our previous animal experiments, we found that caffeic acid phenethyl ester (CAPE) inhibited the early formation of elastase-induced abdominal aortic aneurysms (AAA) in rats. However, its efficacy in the angiotensin II (Ang II)-induced AAA model and the underlying mechanism remain unclear. Therefore, the primary aim of this study was to further validate the potential mechanism of CAPE through in vivo and in vitro experiments utilizing Ang II.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.