Biomed Res Int. 2014;2014:145342. doi: 10.1155/2014/145342. Epub 2014 May 29.
Caffeic acid phenethyl ester and therapeutic potentials.
Murtaza G1, Karim S2, Akram MR3, Khan SA1, Azhar S1, Mumtaz A4, Bin Asad MH1.
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Abstract
Caffeic acid phenethyl ester (CAPE) is a bioactive compound of propolis extract. The literature search elaborates that CAPE possesses antimicrobial, antioxidant, anti-inflammatory, and cytotoxic properties. The principal objective of this review article is to sum up and critically assess the existing data about therapeutic effects of CAPE in different disorders. The findings elaborate that CAPE is a versatile therapeutically active polyphenol and an effective adjuvant of chemotherapy for enhancing therapeutic efficacy and diminishing chemotherapy-induced toxicities.
PMID: 24971312 PMCID: PMC4058104 DOI: 10.1155/2014/145342
[PubMed – indexed for MEDLINE]
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.