Scientific Research and Publications about BROWN Propolis
•    Brazilian Propolis May Help Treat Amyloid Disease (Brazil, Amyloidosis)*
•    Algerian Propolis Potentiates Doxorubicin Mediated Anticancer Effect Against Human Pancreatic PANC-1 Cancer Cell Line through Cell Cycle Arrest, Apoptosis Induction and P-Glycoprotein Inhibition.*
•    Antibiofilm and Antioxidant Activity of Propolis and Bud Poplar Resins versus Pseudomonas aeruginosa.*
•    Chrysin, a natural and biologically active flavonoid suppresses tumor growth of mouse B16F10 melanoma cells: In vitro and In vivo study.*
•    Effects of ethanol extract of propolis on histopathological changes and anti‐oxidant defense of kidney in a rat model for type 1 diabetes mellitus.*
•    Expression of Osteoprotegrin and Osteoclast Level in Chronic Apical Periodontitis Induced with East Java Propolis Extract.*
•    Effect of different formulations of propolis on mice infected with Trypanosoma cruzi.*
•    Synergistic effect of persica mouthwash and Iranian ethanolic extract of propolis against biofilm formation of oral pathogens (in vitro study).*
•    Mexican Propolis: A Source of Antioxidants and Anti-Inflammatory Compounds, and Isolation of a Novel Chalcone and ε-Caprolactone Derivative.*
•    Propolis volatile compounds: chemical diversity and biological activity: a review.*
•    Synergistic composition comprising propolis and carnosic acid for use in the prevention and treatment of candidiasis.*
•    LC-MS analysis and effects of Malaysian propolis on insulin, glucagon, pancreas and oxidative stress status in streptozotocin-induced diabetic rats.*
•    Anatolian Propolis Prevents Oxalate Kidney Stones: Dramatic Reduction of Crystal Deposition in Ethylene-Glycol-Induced Rat Model
•    Rapid Bactericidal Action of Propolis against Porphyromonas gingivitis.*
•    Propolis: A Smart Supplement for an Intracanal Medicament.*
•    Propolis: A New Alternative for Root Canal Disinfection.*
•    Ex vivo immunomodulatory effect of ethanolic extract of propolis during Celiac Disease: involvement of nitric oxide pathway.*
•    Antitumor Properties of Honeybee Plant-Derived Products: Honey, Propolis and Pollen*
•   Beneficial Effect of Pollen and/or Propolis on the Metabolism of Iron, Calcium, Phosphorus, and Magnesium in Rats with Nutritional Ferropenic Anemia*
•    Antioxidant Activities of Propolis collected from Different Regions of Morocco*
•    Antioxidant Properties and Protective Effect of Turkish Propolis on t-BHP-Induced Oxidative Stress in Foreskin Fibroblast Cells*
•    A New Lignan from Brazilian Propolis.*
•    Antibacterial effect of propolis derived from tribal region on Streptococcus mutans and Lactobacillus acidophilus: An in vitro study.*
•    Effect of Pinocembrin Isolated from Mexican Brown Propolis on Diabetic Nephropathy*
•    Propolis: The future therapy against Helicobacter pylori-mediated gastrointestinal diseases.*
•    Effect of Topical Propolis on Wound Healing Process After Tonsillectomy: Randomized Controlled Study*
•    Comparison of Residual Triple Antibiotic Paste, Propolis and Calcium Hydroxide on Root Canal Walls in Natural Open Apex Teeth: An In Vitro Study
•    Bee Propolis Benefits to Fight Everything From Colds to Cancer*
•    Propolis Protects Endotoxin Induced Acute Lung and Liver Inflammation Through Attenuating Inflammatory Responses and Oxidative Stress*
•    Bioactive components and mechanisms of Chinese poplar propolis alleviates oxidized low-density lipoprotein-induced endothelial cells injury.*
•    Propolis and Its Potential to Treat Gastrointestinal Disorders*
•    Inhibitory effect of propolis on the development of AA amyloidosis.*
•    The Inhibition of Inflammasome by Brazilian Propolis (EPP-AF)*
•    Flavonoids in propolis and poplar resin and their inhibition of α-glucosidase activity.*
•    The cytotoxic effects of propolis on breast cancer cells involve PI3K/Akt and ERK1/2 pathways, mitochondrial membrane potential, and reactive oxygen species generation.*
•    Propolis modulates NOS2/arginase-1 pathway in tropomyosin-induced experimental autoimmune uveitis.*
•    Chemical characterization, antioxidant and antimicrobial activity of propolis obtained from Melipona quadrifasciata quadrifasciata and Tetragonisca angustula stingless bees.*
•    Propolis from Different Geographic Origins Suppress Intestinal Inflammation in a Model of DSS‐Induced Colitis is Associated with Decreased Bacteroides spp. in the Gut.*
•    The Effect of Propolis in Healing Injured Nasal Mucosa: An Experimental Study*
•    Comparative Study with a Lip Balm Containing 0.5% Propolis Special Extract GH 2002 versus 5% Aciclovir Cream in Patients with Herpes Labialis in the Papular/Erythematous Stage: A Single-blind, Randomized, Two-arm Study.*
•    Propolis (Bee Glue) – What It Is And Its Health Benefits*
•    New cycloartane triterpenes from bioactive extract of propolis from Pitcairn Island*
•    Propolis ethanolic extracts reduce adenosine diphosphate induced platelet aggregation determined on whole blood*
•    Antimicrobial Activities of European Propolis Collected from Various Geographic Origins Alone and in Combination with Antibiotics*
•    Dietary Propolis Ameliorates Dextran Sulfate Sodium-Induced Colitis and Modulates the Gut Microbiota in Rats Fed a Western Diet*
•    Hypoglycaemic and Antioxidant Effects of Propolis of Chihuahua in a Model of Experimental Diabetes.*
•    Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock.*
•    To Evaluate the Efficacy of Topical Propolis in the Management of Symptomatic Oral Lichen Planus: A Randomized Controlled Trial.*
•    Propolis restored adiponectin level in type 2 diabetes through PPARγ activation.*
•    Investigation of the Bioactivity of Propolis Against Biofilms, Multi-Drug Resistant Bacteria, and Pseudogymnoascus destructans*
•    Characterization and Biological Evaluation of Propolis from Poland.*
 •    Influence of geographic origin, plant source and polyphenolic substances on antimicrobial properties of propolis against human and honey bee pathogens.*
•    Botanic origin and antioxidant activities of a Propolis from Irano-Turanian region as Nutritional Supplements* 
•    Enhancing of Osseointegration with Propolis-Loaded TiO₂ Nanotubes in Rat Mandible for Dental Implants.* 
•    Propolis May Help Protect Against Radiation Damage*
•    Chemical composition and antifungal potential of Brazilian propolis against Candida spp.*
•    Antifungal activity and influence of propolis against germ tube formation as a critical virulence attribute by clinical isolates of Candida albicans.*
•    GC-MS Characterization and Antiulcer Properties of the Triterpenoid Fraction from Propolis of the North West Region of Cameroon*
•    Propolis: a potential natural product to fight Candida species infections.*
•    Antifungal activity of propolis against Candidaspecies isolated from cases of chronic periodontitis.*
   Antifungal activity of propolis extract against yeasts isolated from vaginal exudates.*
 •    Revisiting Greek Propolis: Chromatographic Analysis and Antioxidant Activity Study.*
•    Propolis as a Remedy for Toe Nail Fungus*
•    Inhibitory Effect of Propolis on Platelet Aggregation In Vitro.*
 •    Characteristics, chemical compositions and biological activities of propolis from Al-Bahah, Saudi Arabia.*
•    Effect of Saudi Propolis on Hepatitis Male Rats*
 •    Pinocembrin attenuates allergic airway inflammation via inhibition of NF-κB pathway in mice.*
•    Propolis alleviates concanavalin A-induced hepatitis by modulating cytokine secretion and inhibition of reactive oxygen species.*
 •    Antioxidant, antimicrobial, antiparasitic, and cytotoxic properties of various Brazilian propolis extracts.*
•    Polyphenols as key players for the antileukaemic effects of propolis.*
 •    Antioxidant effects and bioavailability evaluation of propolis extract and its content of pure polyphenols*
•    Antidiabetic effect of propolis: reduction of expression of glucose-6-phosphatase through inhibition of Y279 and Y216 autophosphorylation of GSK-3α/β in HepG2 cells.*
 •    Evaluation of bioactive compounds potential and antioxidant activity of brown, green and red propolis from Brazilian northeast region.*
 •    Propolis and Herba Epimedii extracts enhance the non-specific immune response and disease resistance of Chinese sucker, Myxocyprinus asiaticus.*
•    Mechanisms underlying the wound healing potential of propolis based on its in vitro antioxidant activity.*
•    Propolis reversed cigarette smoke-induced emphysema through macrophage alternative activation independent of Nrf2.*
•    Topical propolis improves wound healing in patients with diabetic foot ulcer: a randomized controlled trial.*
•    The use of Brazilian propolis for discovery and development of novel anti-inflammatory drugs.*
 •    Molecular Mechanism Underlying the Therapeutic Activities of Propolis: A Critical Review*
•    New propolis type from north-east Brazil: chemical composition, antioxidant activity and botanical origin.*
•    The Role of Propolis in Oxidative Stress and Lipid Metabolism: A Randomized Controlled Trial.*
•    Propolis with high flavonoid content collected by honey bees from Acacia paradox.*
•    Propolis and bee health: the natural history and significance of resin use by honey bees*
 •    Chemical compositions and characteristics of organic compounds in propolis from Yemen.*
•    Mechanisms underlying the cytotoxic effect of propolis on human laryngeal epidermoid carcinoma cells.*
•    Metabolomics study of Populus type propolis.*
 •    In Vitro Cytotoxicity of Thai Stingless Bee Propolis from Chanthaburi Orchard*
•    Effects of a new clerodane diterpenoid isolated from propolis on chemically induced skin tumors in mice.*
•    Brazilian propolis: a natural product that improved the fungicidal activity by blood phagocytes.*
•    Biological properties of propolis extracts: Something new from an ancient product.*
•    Microbiological control and antibacterial action of a propolis-containing mouthwash and control of dental plaque in humans.*
•    The Chemical Characterization of Nigerian Propolis samples and Their Activity Against Trypanosoma brucei.*
•    Propolis Diterpenes as a Remarkable Bio-Source for Drug Discovery Development: A Review.*
•    Propolis protects pancreatic β-cells against the toxicity of streptozotocin (STZ).*
•    Isolation and characterization of cytotoxic diterpenoid isomers from propolis.*
•    Does propolis have any effect on non-alcoholic fatty liver disease?*
•    Modifying effects of propolis on MeIQx promotion of rat hepatocarcinogenesis and in a female rat two-stage carcinogenesis model after multiple carcinogen initiation.*
•    The biological activity of propolis-containing toothpaste on oral health environment in patients who underwent implant-supported prosthodontic rehabilitation.*
•    Antioxidant activity of propolis of various geographic origins.*
 •    Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.*
•    Growth inhibitory activity of ethanol extracts of Chinese and Brazilian propolis in four human colon carcinoma cell lines.*
•    Chrysin Attenuates IL-1β-Induced Expression of Inflammatory Mediators by Suppressing NF-κB in Human Osteoarthritis Chondrocytes.*
•    Biological properties of propolis extracts: Something new from an ancient product.*
•    Propolis Inhibits UVA-Induced Apoptosis of Human Keratinocyte HaCaT Cells by Scavenging ROS.*
•    Comparative Evaluation of Clinical and Radiographic Success of Formocresol, Propolis, Turmeric Gel, and Calcium Hydroxide on Pulpotomized Primary Molars: A Preliminary Study.*
•   The Effects of Propolis in Animals Exposed Oxidative Stress*
•   The consumption of propolis and royal jelly in preventing upper respiratory tract infections and as dietary supplementation in children.*
•   Propolis: a new frontier for wound healing?*
 •   Determination of the Mineral Composition and Toxic Element Contents of Propolis by Near Infrared Spectroscopy.*
•    Pulp Inflammation*
•   Effects of bee propolis supplementation on glycemic control, lipid profile and insulin resistance indices in patients with type 2 diabetes: a randomized, double-blind clinical trial.*
•   Urban propolis from San Juan province (Argentina): Ethnopharmacological uses and antifungal activity against Candida and dermatophytes*
•   Polyphenolic fractions of Algerian propolis reverses doxorubicin induced acute renal oxidative stress*
•   Antibacterial Diterpenic Acids from Brazilian Propolis*
•   The effect of propolis on growth inhibition of Helicobacter pylori isolates from peptic ulcer patient.*
•   NEW EMERGING FIELDS OF APPLICATION OF PROPOLIS*
•   How do bees prevent hive infections? The antimicrobial properties of propolis*
•   Protective Effects of Propolis Against the Amitraz Hepatotoxicity in Mice*
 •   THE IMMUNOMODULATORY EFFECT OF PROPOLIS: A REVIEW*
•   The antifungal effect of six commercial extracts of Chilean propolis on Candida spp.*
•   Synergic effect of associated green, red and brown Brazilian propolis extract onto Streptococcus mutans and Streptococcus sanguinis*
•   Use of Propolis in Cancer Research*
•   Seasonal effect on Brazilian propolis antibacterial activity.*
•   Evaluation of the genotoxicity/mutagenicity and antigenotoxicity/antimutagenicity induced by propolis and Baccharis dracunculifolia, by in vitro study with HTC cells.*
•   The effect of bee propolis on oral pathogens and human gingival fibroblasts.*
 •   Propolis: Alternative Medicine for the Treatment of Oral Microbial Diseases*
•   Role of a proprietary propolis-based product on the wait-and-see approach in acute otitis media and in preventing evolution to tracheitis, bronchitis, or rhinosinusitis from nonstreptococcal pharyngitis.*
•   Brown propolis attenuates cerebral ischemia-induced oxidative damage via affecting antioxidant enzyme system in mice.*
•   Studies on the therapeutic effect of propolis along with standard antibacterial drug in Salmonella enterica serovar Typhimurium infected BALB/c mice.*
•   Antifungal activity of propolis against Candida species isolated from cases of chronic periodontitis.*
•   Chrysin, a flavonoid attenuates histological changes of hyperammonemic rats: A dose dependent study.*
•   Propolis, a Constituent of Honey, Inhibits the Development of Sugar Cataracts and High-Glucose-Induced Reactive Oxygen Species in Rat Lenses.*
•   Functional properties of honey, propolis, and royal jelly.*
•   Ethanol-extracted propolis enhances BBN-initiated urinary bladder carcinogenesis via non-mutagenic mechanisms in rats.*
•   A comparison between characterization and biological properties of Brazilian fresh and aged propolis.*
•   Neurochemical factors associated with the antidepressant-like effect of flavonoid chrysin in chronically stressed mice.*
•   Theoretical studies on the hydrogen-bonding interactions between luteolin and water: a DFT approach.*
•   Efficiency of propolis extract against mitochondrial stress induced by antineoplasic agents (doxorubicin and vinblastin) in rats.*
•   Propolis: A Complex Natural Product with a Plethora of Biological Activities That Can Be Explored for Drug Development.*
•   Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B-cell lymphoma cell line.*
•   Chemical composition of propolis from Canada, its antiradical activity and plant origin.*
•   Antibiofilm Activity of Chilean Propolis on Streptococcus mutans Is Influenced by the Year of Collection.*
 •   The ameliorative potential of ethanolic extract of propolis on hematotoxicity and structural neuronal damage in hyperthermia-exposed rats.*
•   Effects of a diet containing Brazilian propolis on lipopolysaccharide-induced increases in plasma plasminogen activator inhibitor-1 levels in mice.*
•   Propolis modulates miRNAs involved in TLR-4 pathway, NF-κB activation, cytokine production and in the bactericidal activity of human dendritic cells.*
•   Brazilian propolis promotes immunomodulation on human cells from American Tegumentar Leishmaniasis patients and healthy donors infected with L. braziliensis.*
•   Bioactive properties of honey with propolis.*
 •   New bioactive chalcones in propolis from El Salvador.*
 •   Bioassay guided purification of the antimicrobial fraction of a Brazilian propolis from Bahia state.*
•   Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile.*
•   Therapeutic effects of propolis essential oil on anxiety of restraint-stressed mice.*
 •   Antibacterial, antifungal and antiviral activity of propolis of different geographic origin.*
•   Effects of encapsulated propolis on blood glycemic control, lipid metabolism, and insulin resistance in type 2 diabetes mellitus rats.*
•   The antibacterial effect of ethanol extract of polish propolis on mutans streptococci and lactobacilli isolated from saliva.*
•   Biological activities of chinese propolis and brazilian propolis on streptozotocin-induced type 1 diabetes mellitus in rats.*
•   Assessment of the mutagenic activity of extracts of brazilian propolis in topical pharmaceutical formulations on Mammalian cells in vitro and in vivo.*
 •   Propolis Is an Efficient Fungicide and Inhibitor of Biofilm Production by Vaginal Candida albicans.*
•   Ethanolic extract of propolis inhibits atherosclerosis in ApoE-knockout mice.*
 •   In vitro antiproliferative/cytotoxic activity on cancer cell lines of a cardanol and a cardol enriched from Thai Apis mellifera propolis.*
•   Immunomodulatory/anti-inflammatory effects of a propolis-containing mouthwash on human monocytes.*
•   Propolis and its constituent caffeic acid suppress LPS-stimulated pro-inflammatory response by blocking NF-κB and MAPK activation in macrophages.*
•   Review of the biological properties and toxicity of bee propolis (propolis).*
•   Effects of a diet containing Brazilian propolis on lipopolysaccharide-induced increases in plasma plasminogen activator inhibitor-1 levels in mice.*
•   Protective Effect of Propolis Extract on Pancreatic β Cell under Oxidative Stress in vitro.*
•   Propolis Inhibits Neurite Outgrowth in Differentiating SH-SY5Y Human Neuroblastoma Cells*
•   Ethanol-Extracted Brazilian Propolis Exerts Protective Effects on Tumorigenesis in Wistar Hannover Rats.*
•   Turkish propolis protects human endothelial cells in vitro from homocysteine-induced apoptosis.*
•   Polyphenol-Rich Propolis Extracts Strengthen Intestinal Barrier Function by Activating AMPK and ERK Signaling.*
•   Hepatoprotective and Pancreatoprotective Properties of the Ethanolic Extract of Nigerian Propolis.*
•   Anti-catabolic effect of caffeic acid phenethyl ester, an active component of honeybee propolis on bone loss in ovariectomized mice: a micro-computed tomography study and histological analysis.* 
•   Oral supplementation of diabetic mice with propolis restores the proliferation capacity and chemotaxis of B and T lymphocytes towards CCL21 and CXCL12 by modulating the lipid profile, the pro-inflammatory cytokine levels and oxidative stress.*
•   Anti-inflammatory Activity Of Propolis Extracts: A Review* 
•   Propolis modulates miRNAs involved in TLR-4 pathway, NF-κB activation, cytokine production and in the bactericidal activity of human dendritic cells.*
•   Discovery of a Novel Diterpene in Brown Propolis from the State of Parana, Brazil.*
•   Evaluation of the genotoxicity/mutagenicity and antigenotoxicity/antimutagenicity induced by propolis and Baccharis dracunculifolia, by in vitro study with HTC cells.*
•   Antiviral Activity of Hatay Propolis Against Replication of Herpes Simplex Virus Type 1 and Type 2.*
•   Chemical Composition and Biological Activity of Extracts Obtained by Supercritical Extraction and Ethanolic Extraction of Brown, Green and Red Propolis Derived from Different Geographic Regions in Brazil.*   – PDF Available
•   Resveratrol and Propolis as Necrosis or Apoptosis Inducers in Human Prostate Carcinoma Cells*
•   Caffeic Acid Phenethyl Ester Causes p21Cip1 Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells*
•   Caffeic Acid Phenethyl Ester Suppresses the Proliferation of Human Prostate Cancer Cells through Inhibition of p70S6K and Akt Signaling Networks*
•   Antitumor and Anticytopenic Effects of Aqueous Extracts of Propolis in Combination with Chemotherapeutic Agents*
•   Antitumor, Hematostimulative and Radioprotective Action of Water-Soluble derivative of Propolis (WSDP)*
•   Protective effect of brown Brazilian propolis against acute vaginal lesions caused by herpes simplex virus type 2 in mice: involvement of antioxidant and anti-inflammatory mechanisms.*
•   Anti-AIDS agents. 48.(1) Anti-HIV activity of moronic acid derivatives and the new melliferone-related triterpenoid isolated from Brazilian propolis.*
•   The Effects of Propolis and its Isolated Compounds on Cytokine Production by Murine Macrophages*
•   Anti-influenza virus activity of propolis in vitro and its efficacy against influenza infection in mice.*
•   Four di-O-caffeoyl quinic acid derivatives from propolis. Potent hepatoprotective activity in experimental liver injury models.*
•   Potent antihepatotoxic activity of dicaffeoyl quinic acids from propolis.*
•   Cytotoxic, hepatoprotective and free radical scavenging effects of propolis from Brazil, Peru, the Netherlands and China.*
•   Identification of a bioactive compound isolated from Brazilian propolis type 6.*
•   Two novel cytotoxic benzofuran derivatives from Brazilian propolis.*
•   Recent progress in pharmacological research of propolis.*
•   Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines.*
•   Two related cinnamic Acid derivatives from Brazilian honey bee propolis, baccharin and drupanin, induce growth inhibition in allografted sarcoma S-180 in mice.*
•   Identification of caffeoylquinic acid derivatives from Brazilian propolis as constituents involved in induction of granulocytic differentiation of HL-60 cells.*
•   Effect of a new variety of Apis mellifera propolis on mutans Streptococci.*
•   Antimicrobial activity of propolis on oral microorganisms.*
•   In vitro and in vivo effects of isolated fractions of Brazilian propolis on caries development.*
•   New antitumoral agents I: In vitro anticancer activity and in vivo acute toxicity of synthetic 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one and derivatives.*
•   Phenolic compounds from Brazilian propolis with pharmacological activities.*
•   Synthesis and characterization of a metal complex containing naringin and Cu, and its antioxidant, antimicrobial, antiinflammatory and tumor cell cytotoxicity.*
•   Concentration-Dependent Protection by Ethanol Extract of Propolis against γ-Ray-Induced Chromosome Damage in Human Blood Lymphocytes*
•   Antifungal Activity of Brazilian Propolis Microparticles against Yeasts Isolated from Vulvovaginal Candidiasis*
•   Immunomodulatory efficacy of ethanol extract of propolis on tumor-bearing mice with disseminated candidiasis.*
•   Evaluation of estrogenic, antiestrogenic and genotoxic activity of nemorosone, the major compound found in brown Cuban propolis.* – PDF Available
•   Propolis Ethanol Extract Stimulates Cytokine and Chemokine Production through NF-κB Activation in C2C12 Myoblasts.* – PDF Available
•   Novel antidepressant-like activity of propolis extract mediated by enhanced glucocorticoid receptor function in the hippocampus.*  – PDF Available
•   Evaluation of propolis, honey, and royal jelly in amelioration of peripheral blood leukocytes and lung inflammation in mouse conalbumin-induced asthma model.*  – PDF Available
•   Effects of stingless bee propolis on experimental asthma. – PDF Available
•   Biological Properties and Therapeutic Applications of Propolis*

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Scientific Research and Publications about Bee Propolis

Propolis Science information is here to provide you with easy access to research and scientific papers regarding bee propolis. You will find work from respected institutions related to bee propolis in general and also specific types of bee propolis.  The information mentioned here is not offered as specific medical advice for any individual and is not intended to be used for self-diagnosis or treatment. This content should not substitute for medical advice from a health professional. Always consult your healthcare practitioner regarding any health or medical conditions.

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.