J Intercult Ethnopharmacol. 2016 Jan 28;5(1):105-7. doi: 10.5455/jice.20160127024542. eCollection 2016 Jan-Feb.
Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?
Akyol S1, Gulec MA2, Erdemli HK3, Akyol O4.
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Abstract
Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin’s and non-Hodgkin’s lymphoma, Burkitt’s lymphoma, chronic lymphocytic leukemia, Ewing’s sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
PMID: 27069732 PMCID: PMC4805141 DOI: 10.5455/jice.20160127024542
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS IS NOT INTENDED TO DIAGNOSE, TREAT CURE OR PREVENT ANY DISEASE.